Publications

Matz, H.C., Yu, T.G., Zhou, J.Q., Peyton, L., Madsen, A., Han, F., Schmitz, A.J., Horvath, S.C., Dixit, K., Keplinger, H.K., Strnad, B.S., Hoegger, M.J., Middleton, W.D., Klebert, M.K., Lin, N.H., Nachbagauer, R., Paris, R., Turner, J.S., Presti, R.M., Lee, J., Ellebedy, A.H. mRNA-based influenza vaccine expands breadth of B cell response in humans . bioRxiv (2024)

Connor, R.I., Sakharkar, M.I., Rappazao, C.G., Kaku, C.I., Curtis, N.C., Shin, S., Wieland-Alter, W.F., Weiner, J.A., Ackerman, M.E., Walker, L.M., Lee, J., Wright, P.F., Characteristics and functions of infection-enhancing antibodies to the N-terminal domain of SARS-CoV-2 . Pathogens and Immunity (2024)

Araujo, A.M., Dekker, J.D., Garrison, K., Su, Z., Rhee, C., Hu, Z., Lee, B.K., Osorio Hurtado, D., Lee, J., Iyer, V.R., Ehrlich, L.I.R., Georgiou, G., Ippolito, G.C., Yi, S.S., Tucker, H.O., Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice . eLife (2024)

Curtis, N.C.*, Shin, S.*, Hederman, A.P., Connor, R.I., Wieland-Alter, W.F., Ionov, S., Boylston J., Rose, J., Sakharkar, M., Dorman, D.B., Dessaint, J.A., Gwilt, L.L., Crowley, A.R., Feldman, J., Hauser, B., Schmidt, A.G., Ashare, A., Walker, L.M., Wright, P.F., Ackerman, M.E., and Lee, J., Characterization of SARS-CoV-2 Convalescent Patients’ Serological Repertoire Reveals High Prevalence of Iso–RBD Antibodies . bioRxiv (2023)

Kuraoka, M., Curtis, N.C., Watanabe, A., Tanno, H., Shin, S., Ye, K., Macdonald, E., Lavidor, O., Kong, S., Von Holle, T., Windsor, I.W., Ippolito, G.C., Georgiou, G., Walter, E.B., Kelsoe, G.H., Harrison, S.C.*, Moody, M.A.*, Bajic, G.*, and Lee, J.*, Infant antibody repertoires during the first two years of influenza vaccination . mBio (2022)

Crowley A.R., Richardson S.I., Tuyishime M., Jennewein M., Bailey M.J., Lee J., Alter G., Ferrari G., Morris L., and Ackerman M.E., Functional consequences of allotypic polymorphisms in human immunoglobulin G subclasses . Immunogenetics 1-16 (2022)

Crowley, A.R., Natarajan, H., Hederman, A.P., Bobak, C.A., Weiner, J.A., Wieland-Alter, W., Lee, J. , Bloch, E.M., Tobian, A.A.R., Redd, A.D., Blankson, J.N., Wolf, D., Goetghebuer, T., Marchant, A., Connor, R.I., Wright, P.F., and Ackerman, M.E., Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike . eLife 11 (2022)

Ionov, S., and Lee, J., An immunoproteomic survey of the antibody landscape: insights and opportunities revealed by serological repertoire profiling . Front. Immunol. 260 (2022)

Jung, J., Mundle, S.T., Ustyugova, I.V., Horton, A.P., Boutz, D.R., Pougatcheva, S., Prabakaran P., McDaniel, J.R., King, G.R., Park, D., Person, M.D., Ye, C., Tan, B., Tanno, Y., Kim, J.E., Curtis, N.C., DiNapoli, J., Delagrave, S., Ross, T.M., Ippolito, G.C., Kleanthous, H., Lee, J.*, and Georgiou, G.*, Influenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans . J. Clin. Invest. 131, 13 (2021)

McCarthy, R.K., Lee, J., Watanabe, A., Kuraoka, M., Robinson-McCarthy, L.R., Georgiou, G., Kelsoe, G., and Harrison, S.C., A prevalent focused human antibody response to the influenza virus hemagglutinin head interface . mBio 12, 3 (2021)

Butler, S.E., Crowley, A.R., Natarajan, H., Xu, S., Weiner, J.A., Bobak,C.A., Mattox, D.E. Lee, J., Wieland-Alter, W., Connor, R.I., Wright, P.F., and Ackerman, M.E., Distinct features and functions of systemic and mucosal humoral immunity among SARS-CoV-2 convalescent individuals . Front. Immunol. 11, 3797 (2021)

Curtis, N.C., and Lee, J., Beyond bulk single-chain sequencing – getting at the whole receptor . Curr. Opin. Syst. Biol. 24, 93-99 (2020)

Mehaffey, M.R., Lee, J., Jung, J., Lanzillotti, M.B., Escobar, E.E., Morgenstern, K.R., Georgiou, G., and Brodbelt, J.S., Mapping a conformational epitope of hemagglutinin A using native mass spectrometry and ultraviolet photodissociation . Anal. Chem. 92, 17 (2020)

Tanno, H., McDaniel, J.R., Stevens, C.A., Voss, W.N., Li, J., Durrett, R., Lee, J. , Gollihar, J., Tanno, Y., Delidakis, G., Pothukuchy, A., Ellefson, J.W., Goronzy, J.J., Maynard, J.A., Ellington, A.D., Ippolito, G.C., and Georgiou, G. A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires . Sci. Adv. 6, 17 (2020)

Lee, J., Der, B.S., Karamitros, C.S., Wenzong, L., Marshall, N.M., Lungu, O.I., Miklos, A.E., Jianqing, X., Kang, T.H., Lee, C., Tan, B., Hughes, R.A., Jung, S.T., Ippolito, G.C., Gray, J.J., Zhang, Y., Kuhlman, B., Georgiou, G., and Ellington, A.D. Computer-based engineering of thermostabilized antibody fragments . AIChE J. 66, 3 (2020)

Lee, C., Kang, K.H., Gordon, O., Watanabe, M., Delidakis, G., Gillis, C.M., Sterlin, D., Hardy, D., Cogné, M., Macdonald, L.E., Murphy, A.J., Tu, N., Lee, J. , McDaniel, J.R., Makowski, E., Tessier, P.M., Meyer, A.S., Bruhns, P., and Georgiou, G. An engineered human Fc domain that behaves like a pH-toggle switch for ultra-long circulation persistence . Nat. Commun. 10, 5031 (2019)

Lee, J. Molecular-level antibody repertoire profiling and engineering: Implications for developing next-generation diagnostics, therapeutics, and vaccines . Biotechnol. Bioproc. E. 24, 8-11 (2019)